Can J Infect Dis Med Microbiol. Mar-Apr;26(2) Empyema caused by Clostridium bifermentans: A case report. Edagiz S(1), Lagace-Wiens P(2), Embil . Clostridium bifermentans bacteremia resulting in metastatic osteomyelitis involving the sacrum, spine, and ribs. The emergence of resistance of this organism to. We report a case of recurrent Clostridium bifermentans bacteremia resulting in metastatic osteomyelitis involving the sacrum, spine, and ribs. The emergence of .

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Author information Copyright and License information Disclaimer. Histopathology showed infection of the uterus, a site of infection not previously described. She subsequently deteriorated in hospital, with repeat chest radiography demonstrating pulmonary infiltrates and a pneumothorax that appeared to communicate with a cavitary lesion in the chest.

Empyema caused by Clostridium bifermentans: A case report.

Isolation of Clostridium in human infections: Clostridium species are part of the normal flora of the intestinal tract of humans and other animals, and may also be isolated from the female genital tract and the oral mucosa 2. Twenty-nine days after the initial surgical procedure 44 days postadmissionthe patient was taken back to the operating room for a second thoracotomy, right rib resection and empyema drainage.

The aerobic culture did not demonstrate any bacterial growth following 72 h of incubation. In Octobera year-old woman with history of abnormal uterine bleeding status post an uncomplicated endometrial ablation 5 months prior developed new onset dysuria and grayish, malodorous vaginal discharge.

Empyema caused by Clostridium difficile. On respiratory examination, decreased air entry was noted in the right lower and middle lobes. Repeat chest radiography revealed a loculated right-sided pneumothorax with a small amount of fluid remaining in the empyema cavity. Abdominal abscess due to Cardiobacterium hominis and Clostridium bifermentans. Retrieved from ” https: Septic arthritis of the knee due to Clostridium bifermentans. The patient was admitted to hospital.


The patient also complained of sharp right-sided pleuritic chest pain, as well as right upper quadrant abdominal pain associated with deep breathing. This page was last edited on 10 Marchat Thus, to remove potential toxin, empiric plasmapheresis was started on hospital day 3, which showed immediate improvement in hemodynamics, and fluid was able to be removed with continuous venovenous hemofiltration.

Necrotizing pneumonia and empyema caused by Bacillus cereus and Clostridium bifermentans.

The case presented here is similar to the case described by Misra and Hurst 25 in that the infection occurred in the setting of a pulmonary embolus. Jonsson et al 24 described a year-old man who presented with fever, cough and pleuritic chest pain.

Empiric antibiotic therapy with vancomycin, cefepime, and metronidazole was initiated, and she was transferred to the intensive care unit. Alternatively, the infection may have occurred secondary to aspiration, although the patient did not have any risk ibfermentans for aspiration specifically identified.

Published online May C bifermentans was recovered from blood and pleural fluid cultures. Clostridium bifermentans and C.

Clostridium bifermentans (Weinberg and Seguin) Bergey et al. ATCC &reg

On the third day postadmission, the patient continued to complain of significant dyspnea and chest pain. An autopsy demonstrated diffuse edema and evidence of DIC in all organs.

Of note, however, colstridium exchange between large toxin protein producing strains of Clostridium has been previously clostrisium [ 20 ]. Clostridial bacteremia in the community hospital.


She also developed large bilateral pleural effusions and required bilateral chest tube placement with 4 liters per day transudative fluid output. Gas gangrene and other Clostridium -associated diseases. Open in a separate window. This organism is infrequently reported as clostridimu cause of infection in humans, and older publications tended to regard it as nonpathogenic.

She developed profound anasarca, and a repeat pelvic or ophthalmologic exam was unable to be performed because of massive edema.

The constellation of findings in our patient severe capillary leak, profound leukocytosis and hemoconcentration, and improvement with plasmapheresis was very suspicious for C sordellii.

Empyema caused by Clostridium bifermentans: A case report.

Clostridium bifermentans is a rare pathogen in humans. Further characterization of this rare pathogen is warranted. Case report and review of the literature. Several clostridial species have been documented as a cause of pleuropulmonary infection, including Clostridiumm perfringensClostridium sordelliiClostridium sporogenesClostridium paraputrificumClostridium difficileClostridium septicumClostridium cadaveris and Clostridium tetani 19 — WBC, white blood cells. Taxonomy of Clostridium bifermentans and Clostridium sordellii I.

Am J Clin Pathol ; Bifermentanw was afebrile, without rash, and extremities were cool. Arch Intern Med ; It is likely that the increased reporting of this organism reflects, at least in part, improved laboratory methods for detection and identification.

Special stains demonstrated large, boxcar-shaped, Gram-positive rods within endometrial tissue. Clostridium septicum empyema in an immunocompetent woman. Clostridium bifermentans Scientific classification Kingdom: