Atresia auditiva. Algunos bebés nacen sin el conducto auditivo externo o con una malformación del mismo, lo que provoca que padezcan problemas auditivos . ATRANSFERRINEMIA, 95 Atresia biliar, Atresia, bronchial, Atresia Atresia del canalículo lacrimal, Atresia del conducto auditivo externo. Se define como la malformación congénita del oído externo caracterizada por un Atresia. Conducto auditivo. Malformación congénita. Disfunción auditiva.

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This malformation encompasses a wide spectrum of clinical abnormalities of the ear, which differ with regard to its severity, from minor anomalies to the complete absence of the ear or anotia.

This CNV segregates with microtia and other malformations in an autosomal dominant inheritance mode. Denker A, Kahler O, editors. Recently, Li et al. Two new patients and literature review. Clinical, genetic and genomic aspects. Human malformations and related anomalies. When dealing with mutations of only one gene, there is conudcto aggregation and different exyerno of Mendelian inheritance are observed, autosomal recessive, autosomal dominant and X-linked.

Concucto outer ear is formed from six auricular mounds coming from the tissue of the pharyngeal arches I and II. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal’s impact. In summary, information about the association of microtia with mutations or alterations in the amount of major and minor genes and their regulators such as miRNA reveals that there are a large number of loci required in the normal formation of the outer ear.


Humana Press Inc; The one occasionally associated with syndromic entities has important implications with regard to its management, treatment and genetic counseling of the patients. However, the presence of a large number of copies in some genetic regions also can give rise to microtia, as observed in trisomy 13 and 18, but also by the presence of CNV consisting of five copies of a kb amplicon located on the short arm of chromosome 4.

In this case a flap of skin on the external surface of the tympanic membrane was also used. Br J Radiol ; There is also ve that exposure to certain medications such as mycophenolate retinoids and thalidomide cause microtia. A circumferential skin incision is made laterally to the EAC fibrous scar.

Modulo 7 – Fenotipos auriculares y del conducto externo | Flashcards

Standard terminology for the ear. Introduction The medial fibrosis of the external auditory canal EAC is a rare condition in which the medial portion of wuditivo CAE is obliterated with fibrous tissue.

Changes in these genes or in their interactions can lead to the presentation of the malformation. The HOXA2 gene, especially directly related with microtia, 46 is a transcription factor that acts as a gene selector that will express in the morphogenesis of the neural crest and in the second branchial arch, structures that give rise to the formation of the ear.

Am J Otol, 7pp.

This item has received. Due to the relevance that the frequency of microtia auditibo has in different health services in Mexico, it is important that all medical professionals are aware of its clinical, molecular and inherited characteristics.


Modulo 7 – Fenotipos auriculares y del conducto externo

Incisions are performed in the skin with a blade to increase the area and to avoid flap retraction. A CNV could be simple in its structure such as tandem duplication or could imply complex gains or losses of homologous sequences found in multiple sites in the genome.

Attention to this step because the exteerno will undergo some shrinkage. Surgical reconstruction requires formation of a new EAC and new tympanic membrane usually with temporalis fascia. Some failure in genomic or environmental factors or their interactions could cause microtia. It is also important to decrease the risks of frequent infections or exposure to ear toxins caused by some antibiotics that can cause hearing damage that would have been preserved.

Population studies in some European countries and in the Atredia. After application of this surgical technique, the patient is still without recurrence of the disease one and a half year after surgery. Some authors consider microtia to be the minimal expression of this disorder. If you want to submit a manuscript to the journal, please email it to bolmedhospinfantmex gmail.

Its etiology is complex. Prevalence Population studies in some European countries and in the U. The total skin flaps have the advantage of suffering less traction during healing 1 ; however, they have the disadvantage of the larger volume.